A World Where Patients No Longer Die
About
Senno Therapeutics is a biotech company dedicated to developing novel therapies for fatal liver failure using human iPS cell-derived liver progenitor cells and liver organoid technologies.
Senno was founded in 2024 based on iPS cell manipulation technologies developed at the Institute of Medical Science, the University of Tokyo.
We aim to deliver innovative cell therapies that offer patients with liver failure a lifesaving treatment option and alleviate complications from the critical shortage of donor organs.
Company Profile
- Company Name
- Senno Therapeutics Inc.
- Representative
- Chieko Mori, President and Representative Director
- Established
- June 2024
- Capital
- 100,079,970 yen
- Location
- 5-22-33 Higashi-Gotanda, Shinagawa-ku, Tokyo, Japan
Concept
The current reliance on organ transplantation for acute and chronic liver failure leaves a critical unmet need, with many patients dying each year due to the shortage of available organs. Innovative therapies that can address this gap represent a significant opportunity to transform patient outcomes.
Leveraging the iPSC bioengineering infrastructure and expertise developed over the past decade by Professor Hideki Taniguchi’s team at the Institute of Medical Science, the University of Tokyo, Senno is focused on developing cell therapies based on a process that enables the stable synthesis of human iPS cell-derived liver progenitor cells and liver organoids. Our goal is to make it possible for patients with liver disease to receive this potentially curative cell therapy at an early stage and in a minimally invasive manner.
The name “Senno” in Senno Therapeutics is inspired by Sen no Rikyu, a historical figure who established the Japanese tea ceremony. While traditional tea culture had once celebrated the lavish elegance of Chinese influence, Sen no Rikyu introduced a radically original aesthetic called wabi-sabi, which redefined the Japanese tea ceremony as a celebration of simplicity and imperfection.
This concept not only transformed the tea ceremony, but also redefined the spiritual and cultural essence of Japan – an influence which is still evident even today. Sen no Rikyu’s
transformative vision inspires us at Senno to work towards a similarly profound transformation in the treatment of liver disease. Like him, we seek to challenge convention, embrace innovation, and create lasting change by delivering hope and healing to patients who have long had limited options.
Science & Technology
We are discovering and developing novel cell therapies based on our technology platform and manufacturing processes for the stable production of human iPS cell-derived liver progenitor cells and liver organoids.
Team
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Representative Director and CEO
Chieko Mori
Profile -
Scientific Founder and CSO
Hideki Taniguchi
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CTO
Lisa Fox-Craig
Profile -
Associate Director, Project Management
Keisuke Fujitaka
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Corporate planning, Project Management
Yusuke Wada
Profile
Directors
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Representative Director and CEO
Chieko Mori
Profile -
Chairman & Director
Jonathan Yeh
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Board
Hikaru Saito
Profile